I also tested with my Vega 64 in the mix and it crashed the system. I think it loaded the drivers but conflicted with the integrated graphics and panicked. In verbose I could see the 5000kext and 1000controller loading before the crash.
Nice recommendations. I also use Movavi PDF Editor (https://www.movavi.com/pdf-editor-mac/). It's very good for viewing and editing PDF files. They do not have a load of features yet, but they are constantly improving it.