GRUB on MBR booting Linux (and OSX) on GPT drive?

[SilverZero]

Hopefully this is the right board for the answer. I've got two hard drives, primary is using MBR and has a GRUB partition that houses all of the higher-level GRUB stages. I went this route because I have WinXP on this drive, and several Linux sandboxes on the second drive, and I don't want to be messing with GRUB every time I wipe/reinstall/upgrade/break a distro on the other drive. This way, even if I unplugged the second drive and threw it out the window, GRUB would still be there - it's totally unconnected from the second drive.

 

So now, I am thinking it might be good to wipe that second drive, maybe even partition it with a GUID scheme to get more vanilla with my OSX installation. My question is: Will I have any problems with GRUB on the MBR disk trying to boot a kernel (Linux or OSX) on that second GUID disk? Basically, does GRUB have a problem booting GUID partitions?

 

(Optional extra credit question: Does it even matter if I go GUID or MBR if I'm only planning one primary HFS+ partition for OSX and then all logical partitions for Linux?)

 

Thanks!