Here's what is happening to me, and how I resolved it. Maybe it will be of some use. I am having this issue and am running 10.4.8, not 10.4.10.
1. Make sure you install JaS 10.4.8 with the correct hardware for your machine. I had some serious issues with USB with the default installation; once I set up everything correctly it started to work but with some problems. Prior to that, USB wasn't working at all.
After this, USB worked but was sporadic. Anytime I had a USB device plugged in at boot, the system wouldn't boot all the way. Yet occasionally it did work. If I plugged in the USB device once booted, the system slowed to a crawl. Go to step #2.
2. Disable Legacy USB support in your BIOS.
3. Unplug all USB devices and boot your machine.
4. Go to /System/Library/Extensions and drag IOUSBMassStorageClass.kext to your desktop. This will make a copy. Now drag it from /System/Library/Extensions to your Trash and empty it, entering your Admin password.
Once this is done, USB devices (except those in the Mass Storage category) will work. I had to do this to get my USB headphones, keyboard, and trackball to work properly. Otherwise I can't do anything.
As mentioned in another post, the problem may be due to a bad signal received from the USB port that is not handled correctly by MacOS. I will try the updated driver out soon, but for now I used my solution because I needed other functions like audio asap rather than iPods and pen drives.
If you need to reinstall the IOUSBMassStorageClass.kext, just drag it to the correct place, authenticate, then go to Disk Utility and Repair Permissions. If you don't do this, the driver will have the wrong permissions and will throw an error on boot.