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I had a similar issue folllowing the 10.6.5 upgrade plus, I couldn't boot with the new kernel the update installed. I kept getting kernel panics. But as I always keep the old kernel available under the name 'mach_kernel.<O/S version>' I was able to boot to the old kernel, only to find the same problem you have now, no working USB devices, thus no keyboard or mouse. Enabling USBBusFix in my /Extra/com.apple.boot.plist didn't have any impact on my problem but as I have access to other OS X machines, I just pulled the HD, mounted it in a USB case, plugged it into one of the other machines and replaced the 10.6.5 IOUSBFamily.kext and IOUSBMassStorageClass.kexts in /S/L/E with those from 10.6.4. (I first tried putting them in /Extra/Extensions but on booting, I still didn't have any USB devices so I moves them to /S/L/E.) So, I'm running 10.6.5 now but with the kernel and two IOUSB kexts from 10.6.4. My mobo is an ASUS P5QL Pro with a dual-core Pentium CPU