So many people to reply to quoting doesn't make sense on mobile.
No idea about MBA. The newest Mac laptop I have is from 2012 and has no mpcie or m2 slot at all. Though, I would be willing to bet that like the Mac Pro it would require an efi update to the logic board.
I have not tested, but I would be shocked if it booted without an EFI patch to the motherboard. The boot loader runs entirely in the systems EFI and that would require a patch as far as I know. I would test but all my current projects are on that disk. Maybe when I do a fresh instal of the public release of High Sierra I'll try that drive.