QUOTE(Freeser @ Jan 11 2008, 03:11 PM)

I am also in the market for a hard drive for the same reason... is firewire 800 better or esata?
No, eSata destroys firewire 800. PLUS - unless you're running a real Mac, a firewire 800 interface is really difficult to find (firewire 400 is common. eSata is really essentially SATA - just like your internal SATA drives. Here's a comparison:
USB2 = USB 2.0 port rated at 48MB/s
1394a FW400 = FireWire 400 port rated at up to 40MB/s
1394b FW800 = FireWire 800 port rated at up to 80MB/s
SATA = SATA port rated at up to 150MB/s
SATA2 = SATA II port rated at up to 300MB/s
eSata will be either SATA or SATA2 speed, depending on your setup - either way, faster than firewire. (Although it can be argued that a single SATA2 drive never exceeds 150MB/s, etc - but the potential speed is there.)
300MB/s eSata vs 80MB/s firewire 800.
USB is one of the slowest interfaces, but you'll get the most compatibility if you connect your drive to a lot of different computers (older PC's, even some newer PC's, Mac, etc).
Not everyone has an eSata connection, and probably not a free one if they do.
I'm not sure on how common eSata is on Mac's though - so that may be a factor too.
Not all PC's have firewire, and will most likely have firewire400 (arguabley slower than USB - measurements get grey depending on how you calculate) if they do.
One other thing to maybe consider - firewire is the most common way of transferring video/audio from prosumer video cameras. How many firewire ports do you have? If you have only 1, where are you going to dump those large video files?
NOTE - why the heck does is say I just joined today and have only 1 post? I know I don't have many posts - MAYBE this is my first here and it only says "joined" when you make your first post? I do know I joined about 1 year ago, and I do know I did not "register" today - been lurking for many months logged in...I try to keep my mouth shut when I don't know what I'm talking about, and I'm a complete noob to the hackintosh scene...