Crosspost from hardware because I thought somebody would be more likely to help here
I'm using a Midiman USB Keystation 49 on my AMD-based OSx86 10.4.8 comp. It shows up in the Audio MIDI Setup interface but doesn't make any sound in Garageband, Logic Express, or the Audio MIDI Setup test mode. I downloaded the drivers from M-Audio (version 3.2.2 I think). The keyboard works great on my late-model iBook in 10.4.9.