After importing DVD, you will see the figure below.

Setting Introduction
1. Source settings
(1). Title: Handbrake will detect all the titles on the DVD and choose the longest title automatically.
(2). Chapters: By setting chapters' number, you can rip a specific clip. However, this is not very user friendly, since you will have to remember what is on each chapter. If you could preview each chapter, things would be a lot easier.
2. Destination setting: Choose the folder to save ripped movies.
3. Output Settings: select the format and codec you need.
(1). Video Settings

Framerate(FPS): Select a frame rate that you prefer.
Quality:
There are three options available:
1. Specify an output size and the quality will depend on the specified output size.
2. Select a birate. The higher bitrate you choose, the bigger size the output file will be, and the better quality you will get.
3. Directly select a quality.
Encoder: Select the encoder you prefer.
2-pass encoding(optional): This takes twice as long to encode, but it improves the video quality and doesn't make the file any larger.
Picture Settings: Here you can set video resolution and crop video. Different players have different resolution specs. For example, the highest resolution supported by the new nano-chromatic is 640*480. The crop function of handbrake is kind of like a decoration here, because it is not powerful or practical. If this function is important to you, you can refer to a different guide.
(2).Audio Settings

In this section, you can choose audio tracks and movie subtitle, as shown in the above figure.
After all settings done, click Start button to rip.