Here are my major specs:

Gigabyte GA-965p-S3
Core 2 Duo @2.4Ghz
XFX GeForce 7950GT
2GB corsair 800 RAM
D-Link DWA 556 wireless card
2x 250gb WD hard drives

Installed Kalyway 10.5.1 successfully, runs ok, but i have some major problems that i havnt seen with this motherboard on other systems:

1- NVinject kext screws up my system (kernel panic i think), so no graphics drivers
2- Cannot play any videos, they freeze after a few seconds
3- Almost everything i download that has some size to it (even larger torrent files) will not download; i get:
"not enough free disk space"
4- many programs will not download correctly: "not enough disk space"
5- sleep is not working
6- no sound
7- **system hangs (spinning colorwheel) during applications when there is nothing going on

please help, if anyone has encountered any of these that would be great if you could share some advice

thank you

based on the described symptoms, it sounds to me like you've got the wrong graphics drivers... and maybe some serious disk permissions issues. Dunno man, I hope there's some geniuses out there that have answers for ya, because I'm afraid I don't. Have you tried reinstalling?