Seems like the trick for a virgin is to first get it booting Lion. By 1. using a USB boot stick, then 2. a working mac (hackintosh or not) to run the script and patch the boot loader etc. Basically just doing the first 6 steps in the guide in post 1. Once its going you are basically self-sustaining on the deflowered target machine, and can run the script there, only going back to the original helper machine if something goes badly wrong.
If you use a DSDT for the target motherboard from Tonymac's site, just copy and paste into the Extra folder. Or you can use the DSDT patcher (see the Forum Topic by same name a couple of lines down from Tutorial). I don't use DD's script for DSDT or Plist mods.
When I am building for a 'virgin' machine, I configure the harddrive on a working Hack (except for DSDT) and then transfer the HD to the new machine. If I have done the job correctly, the new machine boots into the Mac initial registration screen and I proceed from there. Should it not work, I try to determine the problem and take the HD back to the working machine for modification. Usually most everything works and I can go from bare HD to New Mac working in about 30 minutes. I prefer the 1366 hardware as I find it much more robust and stable than 1155 and 1156. I find it well worth the few extra dollars.
Its been nearly 3 years since this (and ancestors) thread started and Intel brought out their 1366 i7. That original machine has been a real workhorse hasn't it. Still, I was happy to see the z68 i5 1155, and even the mATX GA-Z68MX-UD2H-B3 I'm using somewhat by accident, seem to fairly well supported. There are many detailed hardware lists and builds on tonymacx86 (apparently against the rules to link directly to them here). I didn't go so far as to use #####, but I did look at the build to decide to use Chimera and a starting subset of kexts. Lion seems to be running now using the DD script, so I could rebuild my DSDT, but yeah, I just took the DSDT for my board+BIOS from tonymac and stuffed DSDT.aml into /Extra. I do think these z68 i5 boards are going to become well supported, because in fact Apple uses them in their iMacs. Though, there oughta be a 1366 refresh in 2 - 5 months. Still, at the moment, there's nothing quite like a SATA 3 SSD on those i5 boards, say a Patriot Wildfire or an OCZ Vertex3. And the i5's seem to OC 50% without even trying.
There's a gap between expert threads like this one, and script kiddie GUI tools on tonymac.
Final challenge now is to try to get triple monitors working. There are some new 2012 Dells that have already appeared in Asia like the U2312HM... IPS 23" with LED and thin bezel. Thinking 3 of those rotated 90 degrees like a triptych for $200 each would be better than a single $1000 27" Apple monitor. (That would give me 3240x1920 instead of 2560x1440. There's also a U2412 16:10 for 50% more money that would add up to 3600 pixels wide). Trying to stick to known cards. Some talk on Netkas that some 5xxx and 6xxx ATI cards are OS X supported OOTB.